{"id":592,"date":"2024-07-09T05:17:24","date_gmt":"2024-07-09T11:17:24","guid":{"rendered":"http:\/\/anc.local\/?page_id=592"},"modified":"2024-07-09T05:17:29","modified_gmt":"2024-07-09T11:17:29","slug":"jose-maria-gutierrez-gutierrez","status":"publish","type":"page","link":"https:\/\/www.anc.cr\/en\/jose-maria-gutierrez-gutierrez\/","title":{"rendered":"Jos\u00e9 Mar\u00eda Guti\u00e9rrez Guti\u00e9rrez"},"content":{"rendered":"
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Jos\u00e9 Mar\u00eda Guti\u00e9rrez Guti\u00e9rrez<\/h3>\n\n\n\n

Acad\u00e9mico de N\u00famero<\/p>\n\n\n\n

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  • Profesor Em\u00e9rito, Instituto Clodomiro Picado, Facultad de Microbiolog\u00eda, Universidad de Costa Rica, San Jos\u00e9, Costa Rica.<\/li>\n\n\n\n
  • Licenciado en Microbiolog\u00eda y Qu\u00edmica Cl\u00ednica, Universidad de Costa Rica (1977).<\/li>\n\n\n\n
  • Doctor (PhD) en Ciencias Fisiol\u00f3gicas, Oklahoma State University, USA (1984).<\/li>\n\n\n\n
  • Sab\u00e1tico en el Instituto Butantan, Sao Paulo, Brasil (1996 y 2000). <\/li>\n<\/ul>\n<\/div>\n\n\n\n
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    Jos\u00e9 Mar\u00eda Guti\u00e9rrez es Licenciado en Microbiolog\u00eda y Qu\u00edmica Cl\u00ednica y Doctor en Ciencias Fisiol\u00f3gicas. Durante 45 a\u00f1os fue integrante de la Divisi\u00f3n Acad\u00e9mica del Instituto Clodomiro Picado, de la Universidad de Costa Rica y Profesor Catedr\u00e1tico de la Facultad de Microbiolog\u00eda de dicha universidad, donde imparti\u00f3 docencia de grado y posgrado en Inmunolog\u00eda, M\u00e9todos de Investigaci\u00f3n, Bioqu\u00edmica y Patolog\u00eda Celular. Actualmente es Profesor Em\u00e9rito del Instituto Clodomiro Picado y la Facultad de Microbiolog\u00eda.<\/p>\n\n\n\n

    Sus \u00e1reas de inter\u00e9s en investigaci\u00f3n son la bioqu\u00edmica, inmunolog\u00eda y patolog\u00eda experimental de venenos de serpientes, particularmente el estudio del mecanismo de acci\u00f3n de las toxinas que provocan lesi\u00f3n tisular local en envenenamientos por serpientes de la familia Viperidae. Adem\u00e1s, participa en proyectos para el mejoramiento de los antivenenos utilizados en tratamiento de los envenenamientos of\u00eddicos, en el estudio de la capacidad neutralizante de los antivenenos de diversas regiones del mundo, en el desarrollo de nuevos antivenenos para pa\u00edses que carecen de estos productos y en la b\u00fasqueda de nuevos agentes inhibidores de las toxinas de venenos. Se interesa tambi\u00e9n por temas relacionados con la epidemiolog\u00eda y cl\u00ednica de los envenenamiento of\u00eddicos, as\u00ed como con el desarrollo cient\u00edfico-tecnol\u00f3gico, la historia de la ciencia en Costa Rica y las implicaciones sociales del trabajo cient\u00edfico. <\/p>\n\n\n\n

    Ha sido Director, Subdirector y Coordinador de la Divisi\u00f3n Acad\u00e9mica del Instituto Clodomiro Picado y Director del Programa de Posgrado en Microbiolog\u00eda, Parasitolog\u00eda y Qu\u00edmica Cl\u00ednica, as\u00ed como Coordinador del Programa de Posgrado en Ciencias Biom\u00e9dicas Centroam\u00e9rica Instituto Karolinska. Ha coordinado las actividades de cooperaci\u00f3n internacional del Instituto Clodomiro Picado. Ha fungido como asesor de la Organizaci\u00f3n Mundial de la Salud (OMS) y la Organizaci\u00f3n Panamericana de la Salud OPS) en el tema de antivenenos.   <\/p>\n\n\n\n

    Publicaciones representativas: <\/h3>\n\n\n\n
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    • Guti\u00e9rrez, J.M., Rucavado, A., Escalante, T. & D\u00edaz, C. (2005) Hemorrhage induced by snake venom metalloproteinases: biochemical and biophysical mechanisms involved in microvessel damage.\u00a0 Toxicon 45, 997-1011.<\/li>\n\n\n\n
    • Guti\u00e9rrez, J.M., Rojas, E., Quesada, L., Le\u00f3n, G., N\u00fa\u00f1ez, J., Laing, G.D., Sasa, M., Renjifo, J.M., Nasidi, A., Warrell, D.A., Theakston, R.D.G. & Rojas, G. (2005) Pan-African polyspecific antivenom produced by caprylic acid purification of horse IgG: an alternative to the antivenom crisis in Africa.\u00a0 Transactions of the Royal Society of Tropical Medicine and Hygiene 99, 468-475.<\/li>\n\n\n\n
    • Guti\u00e9rrez, J.M., Williams, D., Fan H.W. & Warrell, D.A. (2010) Snakebite envenoming from a global perspective: Towards an integrated approach. Toxicon 56: 1223-1235.<\/li>\n\n\n\n
    • Hern\u00e1ndez, R., Cabalceta, C., Saravia-Otten, P., Chaves, A., Guti\u00e9rrez, J.M. & Rucavado, A. (2011) Poor regenerative outcome after skeletal muscle necrosis induced by Bothrops asper venom: Alterations in microvasculature and nerves. PLoS ONE 6: e19834.<\/li>\n<\/ul>\n\n\n\n
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      • Guti\u00e9rrez, J.M., Escalante, T., Rucavado, A., Herrera, C. & Fox, J.W. (2016) A comprehensive view of the structural and functional alterations of extracellular matrix by snake venom metalloproteinases (SVMPs): Novel perspectives on the pathophysiology of envenoming. Toxins 8: 304.<\/li>\n\n\n\n
      • Guti\u00e9rrez, J.M., Calvete, J.J., Habib, A.G., Harrison, R.A., Williams, D.J. & Warrell, D.A. (2017) Snakebite envenoming. Nature Reviews Disease Primers 3: 17063.<\/li>\n\n\n\n
      • Guti\u00e9rrez, J.M., Escalante, T., Hern\u00e1ndez, R., Gastaldello, S., Saravia-Otten, P. & Rucavado, A. (2018) Why is skeletal muscle regeneration impaired after myonecrosis induced by viperid snake venoms? Toxins 10: 182.<\/li>\n\n\n\n
      • Guti\u00e9rrez, J.M. (2020) Snakebite envenoming from an Ecohealth perspective. Toxicon X 7: 100043.<\/li>\n<\/ul>\n\n\n\n
          \n
        • Guti\u00e9rrez, J.M. (2021) Snake envenomation as a neglected tropical disease. New impetus for confronting and old scourge. En: Handbook of Venoms and Toxins of Reptiles, 2nd<\/sup>\u00a0Ed. (Mackessy, S.P., Ed.). CRC Press, Boca Raton, Florida, USA, pp. 471-483.<\/li>\n\n\n\n
        • Guti\u00e9rrez, J.M., Vargas, M., Segura, \u00c1., Herrera, M., Villalta, M., Solano, G., S\u00e1nchez, A., Herrera, C. & Le\u00f3n, G. (2021) In vitro tests for assessing the neutralizing ability of snake antivenoms: Toward the 3Rs principles. Frontiers in Immunology 11: 617429.<\/li>\n\n\n\n
        • Guti\u00e9rrez, J.M., Bolon, I., Borri, J. & Ruiz de Casta\u00f1eda, R. (2023) Broadening the research landscape in the field of snakebite envenoming: towards a holistic perspective.\u00a0Toxicon<\/em>\u00a0233<\/strong>: 107279.<\/li>\n\n\n\n
        • Hall, S.R., Rasmussen, S.A., Crittenden, E., Dawson, C.A., Bartlett, K.E., Westhorpe, A.P., Albulescu, L.O., Kool, J., Guti\u00e9rrez, J.M. & Casewell, N.R. (2023) Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms.\u00a0Nature Communications<\/em>\u00a014<\/strong>: 7812.<\/li>\n\n\n\n
        • Bittenbinder, M., van Thiel, J., Cardoso, F.C., Casewell, N.R., Guti\u00e9rrez, J.M., Kool, J. & Vonk, F.J. (2024) Tissue damaging toxins in snake venoms: mechanisms of action, pathophysiology and treatment strategies.\u00a0Communications Biology<\/em>\u00a07<\/strong>: 358.<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"

          Jos\u00e9 Mar\u00eda Guti\u00e9rrez Guti\u00e9rrez Acad\u00e9mico de N\u00famero Jos\u00e9 Mar\u00eda Guti\u00e9rrez es Licenciado en Microbiolog\u00eda y Qu\u00edmica Cl\u00ednica y Doctor en Ciencias Fisiol\u00f3gicas. Durante 45 a\u00f1os fue integrante de la Divisi\u00f3n Acad\u00e9mica del Instituto Clodomiro Picado, de la Universidad de Costa Rica y Profesor Catedr\u00e1tico de la Facultad de Microbiolog\u00eda de dicha universidad, donde imparti\u00f3 docencia de […]<\/p>\n","protected":false},"author":1,"featured_media":488,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-592","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"\nJos\u00e9 Mar\u00eda Guti\u00e9rrez Guti\u00e9rrez - ANC<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.anc.cr\/en\/jose-maria-gutierrez-gutierrez\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Jos\u00e9 Mar\u00eda Guti\u00e9rrez Guti\u00e9rrez - ANC\" \/>\n<meta property=\"og:description\" content=\"Jos\u00e9 Mar\u00eda Guti\u00e9rrez Guti\u00e9rrez Acad\u00e9mico de N\u00famero Jos\u00e9 Mar\u00eda Guti\u00e9rrez es Licenciado en Microbiolog\u00eda y Qu\u00edmica Cl\u00ednica y Doctor en Ciencias Fisiol\u00f3gicas. 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